Medical Dictionary

upstream

adv or adj up·stream \ˈəp-ˈstrēm\

Medical Definition of UPSTREAM

:  in a direction along a molecule of DNA or RNA opposite to that in which transcription and translation take place and toward the end having a phosphate group attached to the position labeled 5′ in the terminal nucleotide <a small coding sequence is located just upstream from each…gene—J. N. Goldman et al>—compare downstream

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