topoisomerase

noun topo·isom·er·ase \ˌtō-pō-ī-ˈsä-mə-ˌrās, -ˌrāz\

Definition of TOPOISOMERASE

: any of a class of enzymes that reduce supercoiling in DNA by breaking and rejoining one or both strands of the DNA molecule

top- + isomerase

First Known Use: 1980

Medical Dictionary

noun topo·isom·er·ase \ˌtō-pō-ī-ˈsäm-ə-ˌrās, -ˌrāz\

: any of a class of enzymes that reduce supercoiling in DNA by breaking and rejoining one or both strands of the DNA molecule

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