Dictionary

substance

noun sub·stance \ˈsəb-stən(t)s\

: a material of a particular kind

: a drug that is considered harmful and whose use is controlled by law or made illegal

: the quality of being meaningful, useful, or important

Full Definition of SUBSTANCE

1
a :  essential nature :  essence
b :  a fundamental or characteristic part or quality
c Christian Science :  god 1b
2
a :  ultimate reality that underlies all outward manifestations and change
b :  practical importance :  meaning, usefulness <the…bill—which will be without substance in the sense that it will authorize nothing more than a set of ideas — Richard Reeves>
3
a :  physical material from which something is made or which has discrete existence
b :  matter of particular or definite chemical constitution
c :  something (as drugs or alcoholic beverages) deemed harmful and usually subject to legal restriction <possession of a controlled substance> <substance abuse>
4
:  material possessions :  property <a family of substance>
sub·stance·less \-ləs\ adjective
in substance
:  in respect to essentials :  fundamentally

Origin of SUBSTANCE

Middle English, from Anglo-French, from Latin substantia, from substant-, substans, present participle of substare to stand under, from sub- + stare to stand — more at stand
First Known Use: 14th century
SUBSTANCE Defined for Kids

substance

noun sub·stance \ˈsəb-stəns\

Definition of SUBSTANCE for Kids

1
:  material of a certain kind <an oily substance>
2
:  the most basic or important part or quality <The books differ in both style and substance.>
3
:  material belongings :  wealth <a person of substance>
Medical Dictionary

substance

noun sub·stance \ˈsəb-stən(t)s\

Medical Definition of SUBSTANCE

1
:  physical material from which something is made or which has discrete existence <the substance of nerve tissue>
2
:  matter of particular or definite chemical constitution
3
:  something (as alcohol, methamphetamine, or marijuana) deemed harmful and usually subject to legal restriction <heroin is a controlled substance> <substance abuse>
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