First Known Use: 1995
Dictionary
sildenafil
noun sil·den·a·fil \sil-ˈde-nə-ˌfil\
Definition of SILDENAFIL
: a drug used in the form of its citrate C22H30N6O4S‧C6H8O7 to treat erectile dysfunction
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Origin of SILDENAFIL
perhaps by alteration and recombination of letters from sulfonyl, phenyl, and pyrimidine
Medical Dictionary
sildenafil
noun sil·den·a·fil \sil-ˈden-ə-ˌfil\
Medical Definition of SILDENAFIL
: a drug that is used in the form of its citrate C22H30N6O4S·C6H8O7 to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effect on the hormone cyclic GMP, and that enables the cyclic GMP produced during sexual arousal to initiate the muscular and vascular changes which produce an erection—see viagra
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