Dictionary
1mainline
verb main·line \ˈmān-ˌlīn\
: to inject (a drug) directly into a vein
Full Definition of MAINLINE
transitive verb
slang : to take by or as if by injecting into a principal vein
intransitive verb
slang : to mainline a narcotic drug
See mainline defined for English-language learners
First Known Use of MAINLINE
1938
Rhymes with MAINLINE
A-line, affine, airline, align, alkyne, alpine, assign, at sign, balkline, baseline, beeline, benign, bloodline, blue line, blush wine, bovine, bowline, branchline, breadline, bright-line, buntline, bustline, byline, call sign, canine, caprine, carbine, carmine, cervine, chow line, clothesline, cloud nine, coastline, combine, compline, condign, confine, consign, corvine, cosign, cutline, dateline, deadline, decline, define, design, divine, dragline, driveline, earthshine, Einstein, eiswein, end line, enshrine, entwine, equine, ethyne, fall line, fault line, feline, ferine, first-line, flatline, flight line, foul line, fräulein, frontline, front line, goal line, gold mine, grapevine, guideline, hairline, hard-line, hard pine, headline, hemline, high sign, hipline, Holbein, hotline, ice wine, incline, indign, in fine, in-line, Irvine, jawline, jug wine, landline, land mine, lang syne, lifeline, load line, longline, lupine, main line, malign, midline, moline, moonshine, neckline, off-line, old-line, online, opine, outline, outshine, ovine, Pauline, peace sign, Petrine, pipeline, piscine, pitch pine, plotline, plumb line, plus sign, pontine, porcine, potline, pound sign, propine, punch line, rapine, recline, redline, red pine, refine, reline, repine, resign, Rhine wine, ridgeline, roofline, Sabine, saline, Scotch pine, scrub pine, setline, shoreline, short line, sideline, sight line, skyline, snow line, soft-line, spring line, straight-line, strandline, straw wine, streamline, strip mine, strychnine, subline, sunshine, supine, syncline, taurine, tie-line, times sign, topline, touchline, towline, tramline, trapline, tree line, trephine, trotline, truckline, trunk line, tumpline, turbine, untwine, ursine, vespine, V sign, vulpine, waistline, white line, white pine, white wine, woodbine, yard line, zebrine, Z line
2mainline
adjective
: belonging to an established and widely accepted group or system
Full Definition of MAINLINE
: being part of an established group; also : being in the mainstream
See mainline defined for English-language learners
First Known Use of MAINLINE
1941
Medical Dictionary
mainline
verb main·line \ˈmān-ˈlīn\
main·linedmain·lin·ing
Medical Definition of MAINLINE
transitive verb
slang : to take by or as if by injecting into a principal vein
intransitive verb
slang : to mainline a narcotic drug (as heroin)
Seen & Heard
What made you want to look up mainline? Please tell us where you read or heard it (including the quote, if possible).