Medical Dictionary

downregulation

noun down·reg·u·la·tion \ˈdan-ˌreg-yə-ˈlā-shən\

Medical Definition of DOWNREGULATION

:  the process of reducing or suppressing a response to a stimulus; specifically :  reduction in a cellular response to a molecule (as insulin) due to a decrease in the number of receptors on the cell surface
down·reg·u·late \-ˈreg-yə-ˌlāt\ verb, down·reg·u·lat·ed down·reg·u·lat·ing

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