disaffect

estrange, alienate, disaffect mean to cause one to break a bond of affection or loyalty. estrange implies the development of indifference or hostility with consequent separation or divorcement <his estranged wife>. alienate may or may not suggest separation but always implies loss of affection or interest <managed to alienate all his coworkers>. disaffect refers especially to those from whom loyalty is expected and stresses the effects (as rebellion or discontent) of alienation without actual separation <troops disaffected by hunger>.