First Known Use: circa 1623
Dictionary
agonist
noun ag·o·nist \ˈa-gə-nist\
Definition of AGONIST
1
: one that is engaged in a struggle
2
[from antagonist] a : a muscle that is controlled by the action of an antagonist with which it is paired b : a chemical substance capable of combining with a specific receptor on a cell and initiating the same reaction or activity typically produced by the binding endogenous substance <dopaminergic agonists> — compare antagonist 2b
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Origin of AGONIST
Late Latin agonista competitor, from Greek agōnistēs, from agōnizesthai to contend, from agōn
Medical Dictionary
agonist
noun ag·o·nist \ˈag-ə-nəst\
Medical Definition of AGONIST
1
: a muscle that on contracting is automatically checked and controlled by the opposing simultaneous contraction of another muscle—called also agonist muscle, prime mover; compare antagonist a, synergist 2
2
: a chemical substance (as a drug) capable of combining with a receptor on a cell and initiating the same reaction or activity typically produced by the binding of an endogenous substance <binding of adrenergic agonists>—compare antagonist b
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